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當(dāng)前位置:南京科佰生物科技有限公司>>藥靶細(xì)胞株>>kinase激酶細(xì)胞株>> CBP73223EGFR H773_V774insPHPH/BaF3

EGFR H773_V774insPHPH/BaF3

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產(chǎn)品型號(hào)CBP73223

品牌cobioer/科佰生物

廠商性質(zhì)代理商

所在地南京市

更新時(shí)間:2022-08-02 10:38:53瀏覽次數(shù):698次

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供貨周期 現(xiàn)貨 規(guī)格 T-25 Flask
貨號(hào) CBP73223 應(yīng)用領(lǐng)域 生物產(chǎn)業(yè)
主要用途 僅限科研使用
EGFR H773_V774insPHPH/BaF3,母細(xì)胞:BaF3,凍存條件:90% FBS+10% DMSO
CBP73223
I. Introduction

Cell Line Name:

EGFR H773_V774insPHPH/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative

II.Background

EGFR (HER1), epidermal growth factor receptor, is a tyrosine kinase receptor, which activates RAS/RAF/MEK and PI3K/AKT/mTOR pathways, leading to increased cell proliferation and growth (PMID: 24312144). EGFR activating mutations, amplification, and overexpression are found in a variety of tumors, including non-small cell lung cancer (PMID: 26609494, PMID: 30284706) and colorectal cancer (PMID: 30243897), and the EGFRvIII variant is commonly found in glioblastoma (PMID: 30201736).

III. Representative Data

1. WB of EGFR H773_V774insPHPH/BaF3

CBP73223-1.jpg

2. Anti-proliferation assay


CD74-ROS1 G2032R BaF3

CD74-ROS1 [G2032R] BaF3

CD74-ROS1 L2086F BaF3

CD74-ROS1 [L2086F] BaF3

KRAS G12D&Y96C BaF3

KRAS [G12D&Y96C] BaF3

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