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當(dāng)前位置:南京科佰生物科技有限公司>>藥靶細(xì)胞株>>GPCR細(xì)胞株>> CBP71336CCR4/Ga15/CHO

CCR4/Ga15/CHO

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產(chǎn)品型號(hào)CBP71336

品牌cobioer/科佰生物

廠商性質(zhì)代理商

所在地南京市

更新時(shí)間:2023-11-06 14:47:45瀏覽次數(shù):1139次

聯(lián)系我時(shí),請(qǐng)告知來(lái)自 化工儀器網(wǎng)
供貨周期 現(xiàn)貨 規(guī)格 T-25 Flask
貨號(hào) CBP71336 應(yīng)用領(lǐng)域 生物產(chǎn)業(yè)
主要用途 僅限科研使用
CCR4/Ga15/CHO 凍存條件:90% FBS+10% DMSO
CBP71336
I. Background

C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene.The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines:CCL2 (MCP-1) CCL4 (MIP-1) CCL5 (RANTES) CCL17 (TARC) CCL22 (Macrophage-derived chemokine). Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.


II. Introduction
Host Cell:

CHO

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12K+10%FBS+100μg/ml Hygromycin B+200μg/ml G418
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CCR4 receptor

Transducer:Gi

Ⅲ. Description of Host Cell Line
Organism:Hamster
Tissue:Ovary
Morphology: Epithelial
Growth Properties: Adherent

Ⅳ. Representative Data

CBP71336 數(shù)據(jù)新.jpg

Figure 1. Dose Response of Recombinant Human CCL22 in CCR4/Gα15 CHO cells(C11).



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