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K2-0801-抗dsRNA單克隆抗體—K2抗體
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- 已獲點(diǎn)擊：
- 2025年5月11日
- 2025年11月11日
- 北京北京市
- 匈牙利
- 319次
【產(chǎn)品簡介】
【詳細(xì)說明】
Antibodies - K2
K2單克隆抗體—抗dsRNA抗體
K2單克隆抗體，lgM亞型，是抗dsRNA的單克隆抗體。
K2抗體主要用于一些特殊的檢測。K2抗體主要用于ELISA和夾心法ELISA實(shí)驗(yàn)，一般來說，K2抗體只能用于檢測IgG（IgG2a）亞型抗體不適合的雙鏈RNA（dsRNA）。
K2抗體需干冰運(yùn)輸，因?yàn)楦邼舛鹊腒2抗體容易發(fā)生凝聚，因?yàn)椴蝗菀鬃龀蓛龈煞郏荒艹剡\(yùn)輸。
K2 anti-dsRNA monoclonal antibody has an IgM isotype.
K2 is mainly used for specialised applications, where J2 and K1 - antibodies that can be shipped at ambient temperature - do not suffice. Due to its IgM isotype K2 is more prone to aggregation at high concentration, and therefore cannot be lyophilised and needs to be shipped on ice.
K2 has primarily been used in ELISA and sandwich ELISA. Generally, K2 can be used in applications where an anti-dsRNA antibody with an isotype other than IgG (IgG2a) is required.
參考文獻(xiàn)
Schönborn, J., Oberstrass, J., Breyel, E., Tittgen, J., Schumacher, J. and Lukacs, N. (1991) Monoclonal antibodies to double-stranded RNA as probes of RNA structure in crude nucleic acid extracts. Nucleic Acids Res.19, 2993-3000.
Lukacs, N. (1994) Detection of virus infection in plants and differentiation between coexisting viruses by monoclonal antibodies to double-stranded RNA. J. Virol. Methods 47, 255-272.
Lukacs, N. (1997) Detection of sense:antisense duplexes by structure-specific anti-RNA antibodies. In: Antisense Technology. A Practical Approach, C. Lichtenstein and W. Nellen (eds), pp. 281-295. IRL Press, Oxford.