目錄:杭州斯達(dá)特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B5178Rat Anti-Mouse CD140a Antibody (S-R682)
參考價(jià) | ¥ 600 |
參考價(jià) | ¥ 600 |
更新時(shí)間:2025-06-11 09:27:01瀏覽次數(shù):20評(píng)價(jià)
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CD140a, also known as Platelet-Derived Growth Factor Receptor Alpha (PDGFRα), is a cell surface receptor tyrosine kinase that plays a crucial role in various biological processes. It is a member of the receptor tyrosine kinase (RTK) III class and is widely expressed in cells of mesenchymal origin, including fibroblasts, endothelial cells, glial cells, and certain tumor cells. CD140a binds to various isoforms of platelet-derived growth factors (PDGFs) such as PDGF-AA, PDGF-AB, and PDGF-BB, forming homodimers or heterodimers with CD140b (PDGFRβ) to mediate cellular responses. This receptor is involved in cell proliferation, differentiation, migration, and survival, and is essential for embryonic development, wound healing, and the regulation of platelet activation.
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