目錄:杭州斯達(dá)特生物科技有限公司>>抗體/抗原>>病理/IHC抗體>> S0B2147ERG Recombinant Rabbit mAb (SDT-190-65)
參考價(jià) | ¥ 260 |
參考價(jià) | ¥ 260 |
更新時(shí)間:2025-06-12 08:51:50瀏覽次數(shù):15評(píng)價(jià)
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ERG is an ETS family transcription factor (TF) frequently involved in human cancers, including leukemia [PMID: 21664289], prostate cancer [PMID: 16254181] and Ewing’s sarcoma [PMID: 8223458, PMID: 10561219]. It functions as an oncogene through chromosomal translocations or overexpression. In human leukemia, ERG was initially thought to play a role in leukemogenesis based on the t(16;21) translocation in acute myeloid leukemia (AML), leading to formation of the FUS (TLS)-ERG fusion [PMID: 8234289]. In some cases of AML with this translocation, the leukemia exhibits features of acute megakaryoblastic leukemia [PMID: 12091356].
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