目錄:杭州斯達(dá)特生物科技有限公司>>抗體/抗原>>病理/IHC抗體>> S0B2175CD42b Recombinant Rabbit mAb (SDT-R147)
參考價(jià) | ¥ 600 |
參考價(jià) | ¥ 600 |
更新時(shí)間:2025-06-12 08:52:01瀏覽次數(shù):12評(píng)價(jià)
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Platelet glycoprotein Ib alpha chain also known as glycoprotein Ib (platelet), alpha polypeptide or CD42b (Cluster of Differentiation 42b), is a protein that in humans is encoded by the GP1BA gene. Glycoprotein Ib (GPIb) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The GpIb functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V to form the glycoprotein Ib-IX-V complex. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis.
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