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New York esophageal squamous cell carcinoma 1 （NY-ESO-1, CTAG1B） is a cancer-testis antigen and currently a focus of several targeted immunotherapeutic strategies [PMID: 25412843]. It is a protein consisting of 180 amino acids, and its gene is located in the Xq28 region of the X chromosome. As a member of the cancer testis antigen （CTA） family, NY-ESO-1 has been shown to be expressed in spermatogonia, primary spermatocytes, oogonia, and placenta and in a variety of cancers, such as melanoma, ovarian cancer, cervical cancer [PMID: 28025978, PMID: 25917631].