目錄:杭州斯達特生物科技有限公司>>抗體/抗原>>病理/IHC抗體>> S0B2351p21 Waf1/Cip1 Recombinant Rabbit mAb (SDT-1349-71)
p21Cip1 (alternatively p21Waf1), also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a cyclin-dependent kinase inhibitor (CKI) that is capable of inhibiting all cyclin/CDK complexes [PMID: 8259214], though is primarily associated with inhibition of CDK2 [PMID: 8259214, PMID: 8242751]. p21 represents a major target of p53 activity and thus is associated with linking DNA damage to cell cycle arrest [PMID: 9822382]. his protein is encoded by the CDKN1A gene located on chromosome 6 (6p21.2) in humans.
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