目錄:杭州斯達(dá)特生物科技有限公司>>抗體/抗原>>ELISA試劑盒>> S0C3015Mouse Ig isotype OneStep ELISA Kit
參考價(jià) | ¥ 3200 |
參考價(jià) | ¥ 3200 |
更新時(shí)間:2025-06-13 08:55:38瀏覽次數(shù):21評(píng)價(jià)
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In immunology, antibodies (immunoglobulins (Ig)) are classified into several types called isotypes or classes. The isotype of a primary antibody and the application it is being used in can result in background staining. Primary antibody background noise can be caused by binding to Fc receptors on target cells; by non-specific interactions with cellular proteins, carbohydrates, and lipids; or by cell autofluorescence. There are five antibody isotypes (IgA, IgD, IgE, IgG, and IgM) from mice, same as humans. Each isotype has a different heavy chain. Isotypes are also called classes. Another name for antibodies is immunoglobulin, hence the suffix of 'Ig' to designate antibody classes and subclasses. Naive B cells produce IgM and IgD. During B cell maturation, through isotypic switching, a mature B cell will produce one of IgG, or IgA, or IgE isotypes and subclasses. Different isotypes have different half-lives in vivo, ranging from 12 hours to 8 days.
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