目錄:杭州斯達(dá)特生物科技有限公司>>蛋白>>酶制劑>> UA070039Endo S
| 參考價(jià) | ￥ 1350 |
| 參考價(jià) | ￥ 1350 |
更新時(shí)間：2025-06-16 16:32:42瀏覽次數(shù)：13評(píng)價(jià)
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Anenzyme expressed by Streptococcus pyogenes capable of releasing the
terminal sialic acid residues from glycoproteins such as immunoglobulins.Specifically catalyzes the hydrolysis of the beta-1,4 linkage between
the first two N-acetylglucosamine residues of the complex-type N-linked glycan
located on 'Asn-297' of the Fc region of IgG antibodies （IGHG1, IGHG2, IGHG3 or
IGHG4）, thereby preventing interaction between IgGs and Fc receptors and
ability to activate the complement pathway. Endo S is an endoglycosidase
specific for cleaving the N-linked glycans from the chitobiose core of the
heavy chain of native IgG.
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